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Total posts by Emma E. Fairweather: 4

publication · 11 months ago
Cell-Active Small Molecule Inhibitors of the DNA-Damage Repair Enzyme Poly(ADP-ribose) Glycohydrolase (PARG): Discovery and Optimization of Orally Bioavailable Quinazolinedione Sulfonamides
by Niall M. Hamilton, Emma E. Fairweather, Nicola S. Hamilton, James R. Hitchin, Dominic I. James, Allan M. Jordan, Helen F. Small, Ian D. Waddell, Donald J. Ogilvie, Alison E. McGonagle, Daniel P. Mould, Kate M. Smith, Bohdan Waszkowycz, Louise A. Griffiths, Colin P. Hutton, Stuart Jones, Alexandra I. J. Stowell, Ben Acton, Clifford D. Jones, Julie A. Tucker (The University of Manchester)
publication · 1 year ago
The discovery of 2-substituted phenol quinazolines as potent RET kinase inhibitors with improved KDR selectivity
by Niall M. Hamilton, Emma E. Fairweather, Stuart D. Jones, Allan M. Jordan, Amanda J. Lyons, Helen F. Small, Graeme J. Thomson, Ian D. Waddell, Donald J. Ogilvie, Gemma V. Hopkins, Laura A. Maguire, Daniel P. Mould, Bohdan Waszkowycz, Amanda J. Watson, Alexandra I. J. Stowell, H. Nikki March, Rebecca Newton, Katherine A. Bowler, Emily M. Burns, Philip J. Chapman, Samantha J.R. Fritzl, Kristin M. Goldberg, Sarah V. Holt, Neil Q. McDonald, Andrew G. Purkiss (University of Manchester, Cancer Research UK London Research Institute, Birkbeck College)
publication · 1 year ago
First-in-Class Chemical Probes against Poly(ADP-ribose) Glycohydrolase (PARG) Inhibit DNA Repair with Differential Pharmacology to Olaparib
by Emma E. Fairweather, Nicola S. Hamilton, James R. Hitchin, Dominic I. James, Allan M. Jordan, Ian D. Waddell, Donald J. Ogilvie, Alison E. McGonagle, Kate M. Smith, Bohdan Waszkowycz, Louise A. Griffiths, Colin P. Hutton, Stuart Jones, Paul Kelly, Helen Small, Alexandra I. J. Stowell, Julie Tucker (AstraZeneca, University of Manchester)
publication · 7 years ago
Novel Steroid Inhibitors of Glucose 6-Phosphate Dehydrogenase
by Niall M. Hamilton, Martin Dawson, Emma E. Fairweather, Nicola S. Hamilton, James R. Hitchin, Dominic I. James, Stuart D. Jones, Allan M. Jordan, Amanda J. Lyons, Helen F. Small, Graeme J. Thomson, Ian D. Waddell, Donald J. Ogilvie (Paterson Institute for Cancer Research)