search

Total posts by Kirk E. Hevener: 7

publication · 5 years ago
Fragment-Based Drug Discovery Using a Multidomain, Parallel MD-MM/PBSA Screening Protocol
by Kirk E. Hevener, Michael E. Johnson, Kavankumar Patel, Hyun Lee, Tian Zhu, Hao Lei, Christopher Jones (University of Illinois at Chicago)
publication · 5 years ago
Hit Identification and Optimization in Virtual Screening: Practical Recommendations Based on a Critical Literature Analysis
by Kirk E. Hevener, Michael E. Johnson, Shuyi Cao, Tian Zhu, Pin-Chih Su, Ram Patel, Darshan Shah, Heta B. Chokshi, Richard Szukala (University of Illinois at Chicago)
publication · 5 years ago
Synergistic Inhibitor Binding to the Papain-Like Protease of Human SARS Coronavirus: Mechanistic and Inhibitor Design Implications
by Kirk E. Hevener, Michael E. Johnson, Lena Truong, Kavankumar Patel, Hyun Lee, Shuyi Cao, Joseph L. Gatuz, Arun K. Ghosh (Purdue University, University of Illinois at Chicago)
fragments human SARS coronavirus inhibitors papain-like protease small molecules
publication · 6 years ago
High-level expression, purification, and characterization of Staphylococcus aureus dihydroorotase (PyrC) as a cleavable His-SUMO fusion
by Kirk E. Hevener, Michael E. Johnson, Lena Truong, Amy J. Rice, Kavankumar Patel, Hyun Lee (University of Illinois at Chicago)
publication · 6 years ago
Structural and Enzymatic Analyses Reveal the Binding Mode of a Novel Series of Francisella tularensis Enoyl Reductase (FabI) Inhibitors
by Kirk E. Hevener, Shahila Mehboob, Kent Truong, Teuta Boci, Bernard D. Santarsiero, Michael E. Johnson (University of Illinois at Chicago)
publication · 7 years ago
Structural Studies of Pterin-Based Inhibitors of Dihydropteroate Synthase
by Kirk E. Hevener, Richard E. Lee, Jianjun Qi, Iain D. Kerr, Kerim Babaoglu, Julian G. Hurdle, Kanya Balakrishna, Stephen W. White, Mi-Kyung Yun (University of Tennessee Health Science Center, St. Jude Children’s Research Hospital)
publication · 7 years ago
Quantitative structure-activity relationship studies on nitrofuranyl anti-tubercular agents
by Kirk E. Hevener, David M. Ball, John K. Buolamwini, Richard E. Lee (University of Tennessee Health Science Center)