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Total posts by Nicola S. Hamilton: 4
publication
·
1 year ago
Cell-Active Small Molecule Inhibitors of the DNA-Damage Repair Enzyme Poly(ADP-ribose) Glycohydrolase (PARG): Discovery and Optimization of Orally Bioavailable Quinazolinedione Sulfonamides
by
Niall M. Hamilton
,
Emma E. Fairweather
,
Nicola S. Hamilton
,
James R. Hitchin
,
Dominic I. James
,
Allan M. Jordan
,
Helen F. Small
,
Ian D. Waddell
,
Donald J. Ogilvie
,
Alison E. McGonagle
,
Daniel P. Mould
,
Kate M. Smith
,
Bohdan Waszkowycz
,
Louise A. Griffiths
,
Colin P. Hutton
,
Stuart Jones
,
Alexandra I. J. Stowell
,
Ben Acton
,
Clifford D. Jones
,
Julie A. Tucker
(
The University of Manchester
)
publication
·
2 years ago
First-in-Class Chemical Probes against Poly(ADP-ribose) Glycohydrolase (PARG) Inhibit DNA Repair with Differential Pharmacology to Olaparib
by
Emma E. Fairweather
,
Nicola S. Hamilton
,
James R. Hitchin
,
Dominic I. James
,
Allan M. Jordan
,
Ian D. Waddell
,
Donald J. Ogilvie
,
Alison E. McGonagle
,
Kate M. Smith
,
Bohdan Waszkowycz
,
Louise A. Griffiths
,
Colin P. Hutton
,
Stuart Jones
,
Paul Kelly
,
Helen Small
,
Alexandra I. J. Stowell
,
Julie Tucker
(
AstraZeneca
,
University of Manchester
)
publication
·
7 years ago
Toxoflavins and Deazaflavins as the First Reported Selective Small Molecule Inhibitors of Tyrosyl-DNA Phosphodiesterase II
by
Niall M. Hamilton
,
Nicola S. Hamilton
,
James R. Hitchin
,
Allan M. Jordan
,
Helen F. Small
,
Graeme J. Thomson
,
Ian D. Waddell
,
Donald J. Ogilvie
,
Ali Raoof
,
Paul Depledge
,
Gemma V. Hopkins
,
Laura A. Maguire
,
Alison E. McGonagle
,
Daniel P. Mould
,
Mathew Rushbrooke
,
Kate M. Smith
,
Fabrice Turlais
,
Bohdan Waszkowycz
,
Amanda J. Watson
(
University of Manchester
,
Wolfson Institute for Biomedical Research
)
publication
·
8 years ago
Novel Steroid Inhibitors of Glucose 6-Phosphate Dehydrogenase
by
Niall M. Hamilton
,
Martin Dawson
,
Emma E. Fairweather
,
Nicola S. Hamilton
,
James R. Hitchin
,
Dominic I. James
,
Stuart D. Jones
,
Allan M. Jordan
,
Amanda J. Lyons
,
Helen F. Small
,
Graeme J. Thomson
,
Ian D. Waddell
,
Donald J. Ogilvie
(
Paterson Institute for Cancer Research
)