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Total posts by Stephan C. Schürer: 10

publication · 10 months ago
BioAssay Ontology Annotations Facilitate Cross-Analysis of Diverse High-Throughput Screening Data Sets
by Stephan C. Schürer, Robin Smith, Uma Vempati, Mark Southern, Vance Lemmon (The Scripps Research Institute, University of Miami)
publication · 10 months ago
Ligand-Binding Pocket Shape Differences between Sphingosine 1-Phosphate (S1P) Receptors S1P1 and S1P3 Determine Efficiency of Chemical Probe Identification by Ultrahigh-Throughput Screening
by Pedro J. Gonzalez-Cabrera, Marie-Therese Schaeffer, Jacqueline Chapman, Euijung Jo, Peter Chase, Tim Spicer, Peter Hodder, Hugh Rosen, Stephan C. Schürer, Steven J. Brown (The Scripps Research Institute)
publication · 10 months ago
Large-Scale Computational Screening Identifies First in Class Multitarget Inhibitor of EGFR Kinase and BRD4
by Stephan C. Schürer, Bryce K. Allen, Saurabh Mehta, Ernst Schönbrunn, Stewart W. J. Ember, Nagi Ayad (University of Miami, Delhi Technological University, H. Lee Moffitt Cancer Center and Research Institute)
publication · 10 months ago
Identification of a Novel Class of BRD4 Inhibitors by Computational Screening and Binding Simulations
by Stephan C. Schürer, Bryce K. Allen, Saurabh Mehta, Stuart W. J. Ember, Jin-Yi Zhu, Ernst Schönbrunn, Nagi G. Ayad (University of Miami, Delhi Technological University, H. Lee Moffitt Cancer Center and Research Institute)
publication · 10 months ago
An Overview of the Challenges in Designing, Integrating, and Delivering BARD: A Public Chemical-Biology Resource and Query Portal for Multiple Organizations, Locations, and Disciplines
by Noel Southall, Tudor I. Oprea, Rajarshi Guha, Jeremy J. Yang, Stephan C. Schürer, Andrea de Souza, Joshua A. Bittker, David A. Lahr, Steve Brudz, Simon Chatwin, Anna Waller, Uma D. Vempati, Mark R. Southern, Eric S. Dawson, Paul A. Clemons, Thomas D.Y. Chung (The Scripps Research Institute, University of Miami, Broad Institute of Harvard and MIT, University of New Mexico Health Sciences Center, Vanderbilt University Medical Center, Sanford|Burnham Medical Research Institute)
publication · 4 years ago
Chemical Interrogation of the Neuronal Kinome Using a Primary Cell-Based Screening Assay
by Stephan C. Schürer, Vance Lemmon, Hassan Al-Ali, John L. Bixby (University of Miami)
publication · 6 years ago
BioAssay Ontology Annotations Facilitate Cross-Analysis of Diverse High-Throughput Screening Data Sets
by Stephan C. Schürer, Robin Smith, Uma Vempati, Mark Southern, Vance Lemmon (The Scripps Research Institute, University of Miami)
publication · 6 years ago
Novel Kinase Inhibitors by Reshuffling Ligand Functionalities Across the Human Kinome
by Steven Muskal, Stephan C. Schürer, Dušica Vidović (Eidogen-Sertanty, University of Miami)
publication · 6 years ago
Screening informatics
by Stephan C. Schürer, Nicholas F. Tsinoremas (The Scripps Research Institute, University of Miami)
publication · 6 years ago
Ligand-Binding Pocket Shape Differences between Sphingosine 1-Phosphate (S1P) Receptors S1P1 and S1P3 Determine Efficiency of Chemical Probe Identification by Ultrahigh-Throughput Screening
by Stephen J. Brown, Pedro J. Gonzalez-Cabrera, Marie-Therese Schaeffer, Jacqueline Chapman, Euijung Jo, Peter Chase, Tim Spicer, Peter Hodder, Hugh Rosen, Stephan C. Schürer (The Scripps Research Institute)