The pharmaceutical and biotechnology industries continue to experience a greater need for mature and robust cheminformatics workflows. Factors such as the ever growing scope of compound libraries, be they real or virtual, the expansion of distributed teams and remote work, and novel possibilities presented by cloud computing have dramatically enhanced these needs in the last few years. In this presentation, we aim to provide the audience with an up to date account of the status of ChemAxon’s software, the problems it can help you to solve, as well as workflows and use cases that can be enhanced with these digital tools.