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Total posts by AstraZeneca: 16

publication · 1 week ago
Structural Characterization of Agonist Binding to Protease- Activated Receptor 2 through Mutagenesis and Computational Modeling
by Jens Carlsson, Amanda J. Kennedy, Flavio Ballante, Johan R. Johansson, Graeme Milligan, Linda Sundstrom, Anneli Nordqvist (AstraZeneca, Uppsala University, University of Glasgow)
publication · 6 months ago
Orthologue chemical space and its influence on target prediction
by Andreas Bender, Fredrik Svensson, Lewis H. Mervin, Avid M. Afzal, Ola Engkvist, Krishna C. Bulusu, Leen Kalash, Mike A. Firth, Ian Barrett (AstraZeneca, University of Cambridge, AstraZeneca R&D Gothenburg)
publication · 8 months ago
Interpretable correlation descriptors for quantitative structure-activity relationships
by Benson M Spowage, Craig L Bruce, Jonathan D Hirst (AstraZeneca, University of Nottingham)
publication · 11 months ago
First-in-Class Chemical Probes against Poly(ADP-ribose) Glycohydrolase (PARG) Inhibit DNA Repair with Differential Pharmacology to Olaparib
by Emma E. Fairweather, Nicola S. Hamilton, James R. Hitchin, Dominic I. James, Allan M. Jordan, Ian D. Waddell, Donald J. Ogilvie, Alison E. McGonagle, Kate M. Smith, Bohdan Waszkowycz, Louise A. Griffiths, Colin P. Hutton, Stuart Jones, Paul Kelly, Helen Small, Alexandra I. J. Stowell, Julie Tucker (AstraZeneca, University of Manchester)
presentation · 4 years ago
Increase compound collection value and diversity through collaborations, partnerships, and open-innovation
by Thierry Kogej (AstraZeneca)
poster · 6 years ago
Name-to-Structure Converters One Is Not Enough!
by Plamen Petrov (AstraZeneca)
publication · 6 years ago
A System for Encoding and Searching Markush Structures
by David A Cosgrove, Andrew G Leach, Jon Winter, Andrew Poirrette, Keith M. Green (AstraZeneca)
presentation · 6 years ago
Periscope system for encoding and searching chemical Markush structures
by David A Cosgrove, Andrew G Leach, Jon Winter, Andrew Poirrette, Keith M. Green (AstraZeneca)
presentation · 6 years ago
Chemical text mining for current awareness of pharmaceutical patents
by Sorel Muresan, Roger Sayle, Daniel M. Lowe, Paul Hongxing Xie (AstraZeneca, NextMove Software)
publication · 7 years ago
Evaluation of pKa Estimation Methods on 211 Druglike Compounds
by John Manchester, Grant Walkup, Olga Rivin, Zhiping You (AstraZeneca)
presentation · 8 years ago
Automated spelling correction to improve recall rates of name-to-structure tools for chemical text mining
by Sorel Muresan (AstraZeneca)
presentation · 10 years ago
Complementarity between Public and Commercial Databases of Bioactive Compounds
by Sorel Muresan (AstraZeneca)
presentation · 10 years ago
The Pistoia Alliance: An Emerging Cross-pharma Collaboration
by Ashley George, Debra Igo, Kevin Hebbel, Nick Lynch, Thomas Mueller, Matthias Nolte (Pfizer, GlaxoSmithKline, AstraZeneca, Novartis, chemITment)
presentation · 11 years ago
IBEX - access and exploit SAR data from patents and journals
by Péter Várkonyi (AstraZeneca)
poster · 13 years ago
Web Interface to Dictionary of Natural Products© at Astra Zeneca
by Péter Várkonyi (AstraZeneca)
poster · 14 years ago
CLASS - A High-Throughput Cheminformatic Tool for Chemical Library Profiling
by Sorel Muresan, Paul Xie, Jin Li (AstraZeneca, Chemical Computing)