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Total posts by Université de Lille: 11

publication · 3 weeks ago
A novel codrug made of the combination of ethionamide and its potentiating booster: synthesis, self-assembly into nanoparticles and antimycobacterial evaluation
by Didier Desmaële, Alexandra Pastor, Arnaud Machelart, Xue Li, Nicolas Willand, Alain Baulard, Priscille Brodin, Ruxandra Gref (Université Paris-Sud, Centre National pour la Recherche Scientifique (CNRS), Université de Lille)
publication · 3 weeks ago
A phenotypic approach to the discovery of compounds that promote non-amyloidogenic processing of the amyloid precursor protein: Toward a new profile of indirect b-secretase inhibitors
by Marion Gay, Caroline Evrard, Florian Descamps, Pascal Carato, Nicolas Renault, Mathilde Coevoet, Sabiha Eddarkaoui, Catherine Baud, Paul-Emmanuel Larchanche, Luc Buee, Jamal El Bakali, Valerie Vingtdeux, Nicolas Sergeant, Patricia Melnyk (Université de Lille)
publication · 6 years ago
Ester prodrugs of ciprofloxacin as DNA-gyrase inhibitors: synthesis, antiparasitic evaluation and docking studies
by Bruno Pradines, Christophe Biot, Faustine Dubar, René Wintjens, Rossiane C. Vommaro, Érica S. Martins-Duarte, Wanderley de Souza, Daniel Dive, Christine Pierrot, Alexandre Wohlkonig, Jamal Khalife (Vrije Universiteit Brussel, Universidade Federal do Rio de Janeiro, Institut de Recherche Biomédical des Armées, Université de Lille)
publication · 7 years ago
Antimalarial versus Cytotoxic Properties of Dual Drugs Derived From 4-Aminoquinolines and Mannich Bases: Interaction with DNA
by Reto Brun, Nicole I. Wenzel, Natascha Chavain, Yulin Wang, Wolfgang Friebolin, Louis Maes, Bruno Pradines, Michael Lanzer, Vanessa Yardley, Christel Herold-Mende, Christophe Biot, Katalin Toth, Elisabeth Davioud-Charvet (University of Heidelberg, University of Antwerp, German Cancer Research Center, Université de Lille)
publication · 7 years ago
Stochastic versus Stepwise Strategies for Quantitative Structure-Activity Relationship GenerationHow Much Effort May the Mining for Successful QSAR Models Take?
by Dragos Horvath, Fanny Bonachera, Alexandre Varnek, Vitaly Solovev, Cedric Gaudin (Université de Lille)
publication · 7 years ago
Separation of nucleoside phosphoramidate diastereoisomers by high performance liquid chromatography and capillary electrophoresis
by Catherine Foulon, Claude Vaccher, Jean Bonte-Paul, Jean Goossens-Francois, S. Roux, David Egron, Christian Perigaud (Université de Lille)
publication · 7 years ago
Determination of pKa values of benzoxa-, benzothia- and benzoselena-zolinone derivatives by capillary electrophoresis: Comparison with potentiometric titration and spectrometric data
by Catherine Foulon, Nathalie Duhal, Lacroix- Brigitte Callens, Claude Vaccher, Jean Bonte-Paul, Jean Goossens-Francois (Université de Lille)
publication · 7 years ago
Fuzzy Tricentric Pharmacophore Fingerprints. 2. Application of Topological Fuzzy Pharmacophore Triplets in Quantitative Structure? Activity Relationships
by Dragos Horvath, Fanny Bonachera (Université de Lille)
publication · 7 years ago
Fuzzy tricentric pharmacophore fingerprints. 1. Topological fuzzy pharmacophore triplets and adapted molecular similarity scoring schemes
by Dragos Horvath, Fanny Bonachera, Benjamin Parent, Frédérique Barbosa, Nicolas Froloff (Cerep, Université de Lille)
publication · 7 years ago
A short series of antidiabetic sulfonylureas exhibit multiple ligand PPARγ-binding patterns
by Alban Arrault, Stéphane Rocchi, Frédéric Picard, Pierre Maurois, Bernard Pirotte, Joseph Vamecq (Université de Lille)
poster · 13 years ago
Molecular Modelling web server: A reagents database & tool for drug discovery
by Fanny Bonachera (Université de Lille)