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Total posts by University of Miami: 14

presentation · 1 month ago
A novel platform to identify synergistic drug combination to combat cancer recurrence and prolong clinical efficacy
by Stephan Schurer (University of Miami)
publication · 1 year ago
BioAssay Research Database (BARD): chemical biology and probe-development enabled by structured metadata and result types
by E.A. Howe, A. de Souza, D.L. Lahr, S. Chatwin, P. Montgomery, B.R. Alexander, D.-T. Nguyen, Y. Cruz, D.A. Stonich, G. Walzer, J.T. Rose, S.C. Picard, Z. Liu, J.N. Rose, X. Xiang, J. Asiedu, D. Durkin, J. Levine, J.J. Yang, S.C. Schurer, J.C. Braisted, N. Southall, M.R. Southern, T.D.Y. Chung, S. Brudz, C. Tanega, S.L. Schreiber, J.A. Bittker, R. Guha, P.A. Clemons (University of New Mexico, The Scripps Research Institute, Broad Institute, University of Miami, National Center for Advancing Translational Sciences (NCATS), National Institutes of Health (NIH), Burnham Medical Research Institute)
publication · 1 year ago
DD-01. Ligand and Structure-Based Virtual Screening to Discover Polypharmacological Dual EGFR and BRD4 Inhibitors
by Stephan Schurer, Saurabh Mehta, Nagi Ayad, Bryce Allen (University of Miami)
publication · 1 year ago
BioAssay Ontology Annotations Facilitate Cross-Analysis of Diverse High-Throughput Screening Data Sets
by Stephan C. Schürer, Robin Smith, Uma Vempati, Mark Southern, Vance Lemmon (The Scripps Research Institute, University of Miami)
publication · 1 year ago
Large-Scale Computational Screening Identifies First in Class Multitarget Inhibitor of EGFR Kinase and BRD4
by Stephan C. Schürer, Bryce K. Allen, Saurabh Mehta, Ernst Schönbrunn, Stewart W. J. Ember, Nagi Ayad (University of Miami, Delhi Technological University, H. Lee Moffitt Cancer Center and Research Institute)
publication · 1 year ago
Identification of a Novel Class of BRD4 Inhibitors by Computational Screening and Binding Simulations
by Stephan C. Schürer, Bryce K. Allen, Saurabh Mehta, Stuart W. J. Ember, Jin-Yi Zhu, Ernst Schönbrunn, Nagi G. Ayad (University of Miami, Delhi Technological University, H. Lee Moffitt Cancer Center and Research Institute)
publication · 1 year ago
An Overview of the Challenges in Designing, Integrating, and Delivering BARD: A Public Chemical-Biology Resource and Query Portal for Multiple Organizations, Locations, and Disciplines
by Noel Southall, Tudor I. Oprea, Rajarshi Guha, Jeremy J. Yang, Stephan C. Schürer, Andrea de Souza, Joshua A. Bittker, David A. Lahr, Steve Brudz, Simon Chatwin, Anna Waller, Uma D. Vempati, Mark R. Southern, Eric S. Dawson, Paul A. Clemons, Thomas D.Y. Chung (The Scripps Research Institute, University of Miami, Broad Institute of Harvard and MIT, University of New Mexico Health Sciences Center, Vanderbilt University Medical Center, Sanford|Burnham Medical Research Institute)
presentation · 1 year ago
Managing chemical structure data in a biologically driven research consortium - can it be FAIR?
by Stephan Schurer (University of Miami)
presentation · 2 years ago
Small Molecules in Big Data: Proceed with Caution!
by Tanya Kelley (University of Miami)
publication · 4 years ago
Chemical Interrogation of the Neuronal Kinome Using a Primary Cell-Based Screening Assay
by Stephan C. Schürer, Vance Lemmon, Hassan Al-Ali, John L. Bixby (University of Miami)
presentation · 6 years ago
LIFE, LIFEwrx and the Library of Integrated Network-Based Cellular Signatures
by Christopher Mader (University of Miami)
publication · 6 years ago
BioAssay Ontology Annotations Facilitate Cross-Analysis of Diverse High-Throughput Screening Data Sets
by Stephan C. Schürer, Robin Smith, Uma Vempati, Mark Southern, Vance Lemmon (The Scripps Research Institute, University of Miami)
publication · 6 years ago
Novel Kinase Inhibitors by Reshuffling Ligand Functionalities Across the Human Kinome
by Steven Muskal, Stephan C. Schürer, Dušica Vidović (Eidogen-Sertanty, University of Miami)
publication · 7 years ago
Screening informatics
by Stephan C. Schürer, Nicholas F. Tsinoremas (The Scripps Research Institute, University of Miami)