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Total posts by University of Michigan: 15

publication · 11 months ago
High-performance virtual screening by targeting a high-resolution RNA dynamic ensemble
by Laura R. Ganser, Janghyun Lee, Atul Rangadurai, Dawn K. Merriman, Megan L. Kelly, Aman D. Kansal, Bharathwaj Sathyamoorthy, Hashim M. Al-Hashimi (University of Michigan, Duke University)
publication · 1 year ago
Conjugates of methylene blue with y-carboline derivatives as new multifunctional agents for the treatment of neurodegenerative diseases
by Rudy J. Richardson, Galina F. Makhaeva, Sofya V. Lushchekina, Natalia P. Boltneva, Vladimir B. Sokolov, Gjumrakch Aliev, Sergey O. Bachurin, Elena F. Shevtsova, Nadezhda V. Kovaleva, Elena V. Rudakova, Ludmila G. Dubova, Vladimir P. Fisenko, Daria V. Vinogradova, Alexey Yu. Aksinenko (Russian Academy of Sciences, University of Michigan, GALLY International Biomedical Research Consulting LLC, University of Atlanta)
publication · 1 year ago
Synthesis, molecular docking and biological evaluation of N,N-disubstituted 2-aminothiazolines as a new class of butyrylcholinesterase and carboxylesterase inhibitors
by Rudy J. Richardson, Galina F. Makhaeva, Sofya V. Lushchekina, Natalia P. Boltneva, Olga G. Serebryakova, Sergey O. Bachurin, Tatyana S. Stupina, Alexey A. Terentiev, Igor V. Serkov, Alexey N. Proshin (Russian Academy of Sciences, University of Michigan)
publication · 1 year ago
High-throughput screens for agonists of bone morphogenetic protein (BMP) signaling identify potent benzoxazole compounds
by Shayna T. J. Bradford, Egon J. Ranghini, Pil H. Lee, Gregory R. Dressler, Edward Grimley (University of Michigan)
publication · 5 years ago
MScreen: An Integrated Compound Management and High Throughput Screening (HTS) Data Storage and Analysis System
by Richard R. Neubig, Paul D. Kirchhoff, Renju T. Jacob, Martha J. Larsen, Scott D. Larsen, David H. Sherman (University of Michigan)
publication · 7 years ago
MScreen: An Integrated Compound Management and High Throughput Screening (HTS) Data Storage and Analysis System
by Richard R. Neubig, Paul D. Kirchhoff, Renju T. Jacob, Martha J. Larsen, Scott D. Larsen, David H. Sherman (University of Michigan)
publication · 7 years ago
Mixed Inhibition of Adenosine Deaminase Activity by 1,3-Dinitrobenzene: A Model for Understanding Cell-Selective Neurotoxicity in Chemically-Induced Energy Deprivation Syndromes in Brain
by Carol A. Fierke, Rudy J. Richardson, Martin A. Philbert, Yipei Wang, Xin Liu, Brandon Schneider, Elaina A. Zverina, Kristen Russ, Sanjeeva J. Wijeyesakere (University of Michigan)
publication · 8 years ago
An Evaluation of Explicit Receptor Flexibility in Molecular Docking Using Molecular Dynamics and Torsion Angle Molecular Dynamics
by Roger S. Armen, Jianhan Chen, Charles L. Brooks III (University of Michigan, Kansas State University)
publication · 8 years ago
The PDBbind Database: Methodologies and Updates
by Xueliang Fang, Shaomeng Wang, Renxiao Wang, Yipin Lu, Chao-Yie Yang (University of Michigan)
publication · 9 years ago
Tunable Machine Vision-Based Strategy for Automated Annotation of Chemical Databases
by Gus R. Rosania, Jungkap Park, Kazuhiro Saitou (University of Michigan)
publication · 9 years ago
Predicting pKa
by Adam C. Lee, Gordon M. Crippen (University of Michigan)
publication · 9 years ago
pKa Prediction of Monoprotic Small Molecules the SMARTS Way
by Adam C. Lee, Jing-yu Yu, Gordon M. Crippen (University of Michigan)
publication · 9 years ago
Simulation-based cheminformatic analysis of organelle-targeted molecules: lysosomotropic monobasic amines
by Xinyuan Zhang, Nan Zheng, Gus R. Rosania (University of Michigan)
publication · 9 years ago
Web-Based Tools for Mining the NCI Databases for Anticancer Drug Discovery
by Xueliang Fang, Lei Shao, Hui Zhang, Shaomeng Wang (University of Michigan)
poster · 9 years ago
M-Screen: An Open-Source, Web-Based Application Package that Integrates Compound Management and High Throughput Screening Data Analysis
by Richard R. Neubig, Martha Larsen, Paul D. Kirchhoff, Renju Jacob (University of Michigan)