Hydrogenation and Conformational Analysis of (1R,2R,6S)-3-Methyl-6-(1-methylethenyl)cyclohex-3-ene-1,2-diol

publication · 11 years ago
by Oleg V. Ardashov, Alexander M. Genaev, Dina V. Korchagina, Konstantin P. Volcho, Nariman F. Salakhutdinov, Irina V. Ilina (Russian Academy of Sciences)
Hydrogenation of (1R,2R,6S)-3-methyl-6-(1-methylethenyl)cyclohex-3-ene-1,2-diol was studied. Nickel chloride–sodium tetrahydridoborate system turned out to selectively reduce the double bond in the isopropenyl group. The results of conformational analysis of (1R,2R,6S)-3-methyl-6-(1-methylethenyl)cyclohex-3-ene-1,2-diol and its partly and completely hydrogenated derivatives were in a good agreement with the NMR data.
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