PASS: prediction of activity spectra for biologically active substances

publication · 8 years ago
by Alexey Lagunin, Alla Stepanchikova, Dmitrii Filimonov, Vladimir Poroikov (Institute of Biomedical Chemistry RAMS)
The concept of the biological activity spectrum was introduced to describe the properties of biologically active substances. The PASS (prediction of activity spectra for substances) software product, which predicts more than 300 pharmacological effects and biochemical mechanisms on the basis of the structural formula of a substance, may be efficiently used to find new targets (mechanisms) for some ligands and, conversely, to reveal new ligand's for some biological targets. We have developed a WWW interface for the PASS software. A WWW server for the on-line prediction of the biological activity spectra of substances has been constructed.
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