As a “virtual” biotechnology company, Nimbus Therapeutics’ operations are entirely enabled through partnering with a wide array of academic and contract research organizations across the globe. Within this model, the coordination of data transfer and integration between multiple partners has historically been a challenge, creating a bottleneck that negatively affected the speed and scalability of the organization. Rebecca Carazza describes in-depth a portion of an automated workflow solution that utilizes ChemAxon technology and KNIME to standardize SDFiles provided to Nimbus through this distributed model. The output is registration ready SDFiles with all required data and formats for database registration.