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Total posts by Niall M. Hamilton: 5

publication · 3 months ago
Cell-Active Small Molecule Inhibitors of the DNA-Damage Repair Enzyme Poly(ADP-ribose) Glycohydrolase (PARG): Discovery and Optimization of Orally Bioavailable Quinazolinedione Sulfonamides
by Niall M. Hamilton, Emma E. Fairweather, Nicola S. Hamilton, James R. Hitchin, Dominic I. James, Allan M. Jordan, Helen F. Small, Ian D. Waddell, Donald J. Ogilvie, Alison E. McGonagle, Daniel P. Mould, Kate M. Smith, Bohdan Waszkowycz, Louise A. Griffiths, Colin P. Hutton, Stuart Jones, Alexandra I. J. Stowell, Ben Acton, Clifford D. Jones, Julie A. Tucker (The University of Manchester)
publication · 1 year ago
The discovery of 2-substituted phenol quinazolines as potent RET kinase inhibitors with improved KDR selectivity
by Niall M. Hamilton, Emma E. Fairweather, Stuart D. Jones, Allan M. Jordan, Amanda J. Lyons, Helen F. Small, Graeme J. Thomson, Ian D. Waddell, Donald J. Ogilvie, Gemma V. Hopkins, Laura A. Maguire, Daniel P. Mould, Bohdan Waszkowycz, Amanda J. Watson, Alexandra I. J. Stowell, H. Nikki March, Rebecca Newton, Katherine A. Bowler, Emily M. Burns, Philip J. Chapman, Samantha J.R. Fritzl, Kristin M. Goldberg, Sarah V. Holt, Neil Q. McDonald, Andrew G. Purkiss (University of Manchester, Cancer Research UK London Research Institute, Birkbeck College)
publication · 1 year ago
Anilinoquinazoline inhibitors of the RET kinase domain—Elaboration of the 7-position
by Niall M. Hamilton, Allan M. Jordan, Amanda J. Lyons, Helen F. Small, Ian D. Waddell, Donald J. Ogilvie, Gemma V. Hopkins, Bohdan Waszkowycz, Habiba Begum, Emma Fairweather, Samantha Fritzl, Kristin Goldberg, H. Nikki March, Rebecca Newton, Swamy Vishwanath, Amanda J. Watso (University of Manchester)
publication · 5 years ago
Toxoflavins and Deazaflavins as the First Reported Selective Small Molecule Inhibitors of Tyrosyl-DNA Phosphodiesterase II
by Niall M. Hamilton, Nicola S. Hamilton, James R. Hitchin, Allan M. Jordan, Helen F. Small, Graeme J. Thomson, Ian D. Waddell, Donald J. Ogilvie, Ali Raoof, Paul Depledge, Gemma V. Hopkins, Laura A. Maguire, Alison E. McGonagle, Daniel P. Mould, Mathew Rushbrooke, Kate M. Smith, Fabrice Turlais, Bohdan Waszkowycz, Amanda J. Watson (University of Manchester, Wolfson Institute for Biomedical Research)
publication · 6 years ago
Novel Steroid Inhibitors of Glucose 6-Phosphate Dehydrogenase
by Niall M. Hamilton, Martin Dawson, Emma E. Fairweather, Nicola S. Hamilton, James R. Hitchin, Dominic I. James, Stuart D. Jones, Allan M. Jordan, Amanda J. Lyons, Helen F. Small, Graeme J. Thomson, Ian D. Waddell, Donald J. Ogilvie (Paterson Institute for Cancer Research)