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Marvin

12 05 2022
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Coupling stabilizers open KV1-type potassium channels

ABSTRACT: The opening and closing of voltage-gated ion channels are regulated by voltage sensors...

13 09 2020
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Leveraging ChemAxon’s technology for future product developments

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13 09 2020
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RInCHI Use Case

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12 09 2020
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Neonicotinoid insecticide design: molecular docking, multiple chemometric approaches, and toxicity relationship with Cowpea aphids

Neonicotinoids are the fastest-growing class of insecticides successfully applied in plant...

12 09 2020
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C-H Functionalizations by Palladium Carboxylates: The Acid Effect

Finding optimal reaction conditions is usually complex, requires many experiments, and is therefore...

12 09 2020
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Nuclear Receptors Database Including Negative Data (NR-DBIND): A Database Dedicated to Nuclear Receptors Binding Data Including Negative Data and Pharmacological Profile

Nuclear receptors (NRs) are transcription factors that regulate gene expression in various...

12 09 2020
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Synthesis, structural, spectroscopic and DFT study on a palladium(II)- N-heterocyclic carbene complex

A new palladium complex with N-heterocyclic carbene (NHC) and phosphine ligands was prepared and...

12 09 2020
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Combined Ligand- and Receptor-Based Virtual Screening Methodology to Identify Structurally Diverse Protein Tyrosine Phosphatase 1B Inhibitors

Protein tyrosine phosphatase 1B (PTP1B) is a potential drug target for diabetes and obesity....

12 09 2020
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Anandamide targets aromatase: A breakthrough on human decidualization

In each menstrual cycle endometrial stromal cells (hESC) proliferate and differentiate into...

12 09 2020
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Cellular Uptake of the Atypical Antipsychotic Clozapine Is a Carrier- Mediated Process

The weak base antipsychotic clozapine is the most effective medication for treating refractory...

12 09 2020
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Terpenoids from Euphorbia pedroi as Multidrug-Resistance Reversers

The phytochemical study of Euphorbia pedroi led to the isolation of a new tetracyclic triterpenoid...

12 09 2020
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Bougainvillea Genus: A Review on Phytochemistry, Pharmacology, and Toxicology

This review discusses the current knowledge of the phytochemistry and in vitro and in vivo...