Power search: How to tune search for efficiency and performance Search parameters to fine-tune matching - Search types - Parameters to allow stricter or more loose matching Selected Examples - Usage of key query features/query drawing - Chemical Terms How to search efficiently - Fingerprint parameters and tuning. - What info can the fingerprint use from a query? Matching outside a database: graphs and tricks - isMatching, findFirst, findNext, FindAll - Pre-matching - Order sensitive hits