Chemaxon blog

12 09 2019
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Combined Ligand and Fragment-based Drug Design of Selective Histone Deacetylase – 6 Inhibitors

Histone deacetylase 6 (HDAC6) is unique hydrolase within HDAC family, having pleiotropic...

12 09 2019
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Rapid membrane permeabilization of Listeria monocytogenes and Escherichia coli induced by antibacterial prenylated phenolic compounds from legumes

Prenylated phenolics from the Fabaceae are promising lead compounds for new antibacterials. Pools...

12 09 2019
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EDCs DataBank: 3D-Structure database of endocrine disrupting chemicals

Endocrine disrupting chemicals (EDCs) are a group of compounds that affect the endocrine system,...

12 09 2019
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Revealing the Conformational Preferences of Proteinogenic Glutamic Acid Derivatives in Solution by 1 H NMR Spectroscopy and Theoretical Calculations

The conformational preferences of proteinogenic glutamic acid esterified (GluOMe) and N-acetylated...