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Neonicotinoid insecticide design: molecular docking, multiple chemometric approaches, and toxicity relationship with Cowpea aphids
Neonicotinoids are the fastest-growing class of insecticides successfully applied in plant...
C-H Functionalizations by Palladium Carboxylates: The Acid Effect
Finding optimal reaction conditions is usually complex, requires many experiments, and is therefore...
Nuclear Receptors Database Including Negative Data (NR-DBIND): A Database Dedicated to Nuclear Receptors Binding Data Including Negative Data and Pharmacological Profile
Nuclear receptors (NRs) are transcription factors that regulate gene expression in various...
Synthesis, structural, spectroscopic and DFT study on a palladium(II)- N-heterocyclic carbene complex
A new palladium complex with N-heterocyclic carbene (NHC) and phosphine ligands was prepared and...
Combined Ligand- and Receptor-Based Virtual Screening Methodology to Identify Structurally Diverse Protein Tyrosine Phosphatase 1B Inhibitors
Protein tyrosine phosphatase 1B (PTP1B) is a potential drug target for diabetes and obesity....
Anandamide targets aromatase: A breakthrough on human decidualization
In each menstrual cycle endometrial stromal cells (hESC) proliferate and differentiate into...
Cellular Uptake of the Atypical Antipsychotic Clozapine Is a Carrier- Mediated Process
The weak base antipsychotic clozapine is the most effective medication for treating refractory...
Terpenoids from Euphorbia pedroi as Multidrug-Resistance Reversers
The phytochemical study of Euphorbia pedroi led to the isolation of a new tetracyclic triterpenoid...
Bougainvillea Genus: A Review on Phytochemistry, Pharmacology, and Toxicology
This review discusses the current knowledge of the phytochemistry and in vitro and in vivo...
Microwave-activated carbons from tucuma (Astrocaryum aculeatum) seed for efficient removal of 2-nitrophenol from aqueous solutions
Activated carbons (ACs) prepared from tucumã seed (Astrocaryum aculeatum) were used for...
Assessment of river sediment toxicity: Combining empirical zebrafish embryotoxicity testing with in silico toxicity characterization
ABSTRACT: Quantitative chemical analyses of 428 organic contaminants (OCs) indicated the presence...
Synthesis, Pharmacology, and Molecular Docking Studies on 6-Desoxo-N-methylmorphinans as Potent Opioid Receptor Agonists
Position 6 of the morphinan skeleton plays a key role in the -opioid receptor (MOR) activity in...