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Coupling stabilizers open KV1-type potassium channels
ABSTRACT: The opening and closing of voltage-gated ion channels are regulated by voltage sensors...
Marvin - the next generation of chemical drawing
Marvin is the next generation chemical drawing tool for chemically intelligent visualization.
Leveraging ChemAxon’s technology for future product developments
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Portfolio Presentation
ChemAxon Portfolio includes Structure Sketching & Depiction, Chemical Search Engines, Chemical Data...
Neonicotinoid insecticide design: molecular docking, multiple chemometric approaches, and toxicity relationship with Cowpea aphids
Neonicotinoids are the fastest-growing class of insecticides successfully applied in plant...
C-H Functionalizations by Palladium Carboxylates: The Acid Effect
Finding optimal reaction conditions is usually complex, requires many experiments, and is therefore...
Nuclear Receptors Database Including Negative Data (NR-DBIND): A Database Dedicated to Nuclear Receptors Binding Data Including Negative Data and Pharmacological Profile
Nuclear receptors (NRs) are transcription factors that regulate gene expression in various...
Synthesis, structural, spectroscopic and DFT study on a palladium(II)- N-heterocyclic carbene complex
A new palladium complex with N-heterocyclic carbene (NHC) and phosphine ligands was prepared and...
Combined Ligand- and Receptor-Based Virtual Screening Methodology to Identify Structurally Diverse Protein Tyrosine Phosphatase 1B Inhibitors
Protein tyrosine phosphatase 1B (PTP1B) is a potential drug target for diabetes and obesity....
Anandamide targets aromatase: A breakthrough on human decidualization
In each menstrual cycle endometrial stromal cells (hESC) proliferate and differentiate into...
Cellular Uptake of the Atypical Antipsychotic Clozapine Is a Carrier- Mediated Process
The weak base antipsychotic clozapine is the most effective medication for treating refractory...