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Terpenoids from Euphorbia pedroi as Multidrug-Resistance Reversers
The phytochemical study of Euphorbia pedroi led to the isolation of a new tetracyclic triterpenoid...
Bougainvillea Genus: A Review on Phytochemistry, Pharmacology, and Toxicology
This review discusses the current knowledge of the phytochemistry and in vitro and in vivo...
Microwave-activated carbons from tucuma (Astrocaryum aculeatum) seed for efficient removal of 2-nitrophenol from aqueous solutions
Activated carbons (ACs) prepared from tucumã seed (Astrocaryum aculeatum) were used for...
Assessment of river sediment toxicity: Combining empirical zebrafish embryotoxicity testing with in silico toxicity characterization
ABSTRACT: Quantitative chemical analyses of 428 organic contaminants (OCs) indicated the presence...
Synthesis, Pharmacology, and Molecular Docking Studies on 6-Desoxo-N-methylmorphinans as Potent Opioid Receptor Agonists
Position 6 of the morphinan skeleton plays a key role in the -opioid receptor (MOR) activity in...
Optimization of Physicochemical Properties for 4‐Anilinoquinoline Inhibitors of Plasmodium falciparum Proliferation
We recently reported the medicinal chemistry reoptimization of a known human tyrosine kinase...
Following the oxidation state of organosulfur compounds with NMR: Experimental data versus DFT calculations and database-powered NMR prediction
The thioether-sulfoxide-sulfone oxidation ladder is a feature significant for drug synthesis and...
Sorption and Desorption Mechanisms of Cationic and Zwitterionic Per- and Polyfluoroalkyl Substances in Natural Soils: Thermodynamics and Hysteresis
Sorption linearity and reversibility are implicit in models for the fate and transport of per- and...
BioTransformer: a comprehensive computational tool for small molecule metabolism prediction and metabolite identifcation
A number of computational tools for metabolism prediction have been developed over the last 20...
Combined molecular docking and QSAR study of fused heterocyclic herbicide inhibitors of D1 protein in photosystem II of plants
Cinnoline, pyridine, pyrimidine, and triazine her-bicides were found be inhibitors of the D1...
Codrug Approach for the Potential Treatment of EML4-ALK Positive Lung Cancer
We report on the synergistic effect of PI3K inhibition with ALK inhibition for the possible...
Allamanda cathartica: A Review of the Phytochemistry, Pharmacology, Toxicology, and Biotechnology
In this work, we explore the current knowledge about the phytochemistry and in vitro and in vivo...