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Aquatic toxicity of several textile dye formulations: Acute and chronic assays with Daphnia magna and Raphidocelis subcapitata
Dyes are widely used in various sectors and can be released into the environment where they persist...
A drug pocket at the lipid bilayer–potassium channel interface
Many pharmaceutical drugs against neurological and cardiovascular disorders exert their therapeutic...
Hybrid Pharmacophore Design, Molecular Docking, Synthesis, and Biological Evaluation of Novel Aldimine-Type Schiff Base Derivatives as Tubulin Polymerization Inhibitor
A series of hybrid aldimine-type Schiff base derivatives including trimethoxyphenyl ring and...
Exploring Modifications of an HIV-1 Capsid Inhibitor: Design, Synthesis, and Mechanism of Action
Recent efforts by both academic and pharmaceutical researchers have focused on the HIV-1 capsid...
Halogen bonding enhances activity in a series of dual 5-HT6/D2 ligands designed in a hybrid bioisostere generation/virtual screening protocol
A novel hybrid bioisostere generation/virtual screening method combined with narrowing of chemical...
Immunomodulatory Action of Substituted 1,3,4-Thiadiazines on the Course of Myocardial Infarction
This review focuses on the biological action of the compounds from the group of substituted...
Toward More Drug Like Inhibitors of Trypanosome Alternative Oxidase
New tools are required to ensure the adequate control of the neglected tropical disease human...
The impact of chloride or bromide ions on the advanced oxidation of atrazine by combined electrolysis and ozonation
Advanced oxidation of atrazine (ATZ) via electrolysis and ozonation separately and in combination...
Bisphosphonate-Linked TrkB Agonist: Cochlea-Targeted Delivery of a Neurotrophic Agent as a Strategy for the Treatment of Hearing Loss
Hearing loss affects more than two-thirds of the elderly population, and more than 17% of all...
From Click Chemistry to Cross-Coupling: Designer Polymers from One Efficient Reaction
Palladium-catalyzed Suzuki−Miyaura cross-coupling was demonstrated to be a versatile reaction...