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    12 09 2019
    < 1 minute

    Analysis of the Ligand Efficiency of 4-Thiazolidinone Derivatives with Antitumor Activity

    Ligand efficiency analysis has been shown to be useful in the selection and optimization of new...

    12 09 2019
    < 1 minute

    Potential of marine natural products against drug-resistant fungal, viral, and parasitic infections

    Antibiotics have revolutionised medicine in many aspects, and their discovery is considered a...

    12 09 2019
    < 1 minute

    LigQ: A Webserver to Select and Prepare Ligands for Virtual 2 Screening

    Virtual screening is a powerful methodology to search for new small molecule inhibitors against a...

    12 09 2019
    < 1 minute

    Machine learning for the prediction of molecular dipole moments obtained by density functional theory

    Machine learning (ML) algorithms were explored for the fast estimation of molecular dipole moments...

    12 09 2019
    < 1 minute

    Human Recombinant VEGFR2D4 Biochemical Characterization to Investigate Novel Anti VEGFR2D4 Antibodies for Allosteric Targeting of VEGFR2

    VEGF-A/VEGFR2 complex is the major signaling pathway involved in angiogenesis and the inhibition of...

    12 09 2019
    < 1 minute

    Synthesis of glyceryl glycosides related to A-type prymnesin toxins

    A suite of glycosylated glycerol derivatives representing various fragments of the glycosylated...

    12 09 2019
    < 1 minute

    Quantum chemistry reveals thermodynamic principles of redox biochemistry

    Thermodynamics dictates the structure and function of metabolism. Redox reactions drive cellular...

    12 09 2019
    < 1 minute

    Synthesis, Docking Simulation, Biological Evaluations and 3D-QSAR Study of 1,4-Dihydropyridines as Calcium Channel Blockers

    Resurgence to target L-type voltage-dependent calcium channels has been applied by the synthesis of...

    12 09 2019
    < 1 minute

    nAPOLI: a graph-based strategy to detect and visualize conserved protein-ligand interactions in large-scale

    Essential roles in biological systems depend on protein-ligand recognition, which is mostly driven...

    12 09 2019
    < 1 minute

    Biological activities of extracts from Aspidosperma subincanum Mart. and in silico prediction for inhibition of acetylcholinesterase

    Species of Aspidosperma are traditionally used to treat malaria, leishmaniasis, microbial, and...

    12 09 2019
    2 minutes

    ISiCLE: A Quantum Chemistry Pipeline for Establishing in Silico Collision Cross Section Libraries

    High-throughput, comprehensive, and confident identifications of metabolites and other chemicals in...

    12 09 2019
    < 1 minute

    QSARs to predict adsorption affinity of organic micropollutants for activated carbon and b-cyclodextrin polymer adsorbents

    The removal of organic micropollutants (MPs) from water by means of adsorption is determined by the...